Antimicrobial agent resistance in bacterial isolates from patients with diarrhea and urinary tract infection in the Sudan.
Journal - The American journal of tropical medicine and hygiene (United States )
Antimicrobial sensitivity tests were performed on four-hundred and ninety-seven bacterial isolates from Sudanese patients with diarrhea or urinary tract infections. Shigella dysenteriae type I and enteropathogenic Escherichia coli showed high resistance rates (percentage of isolates showing antibiotic resistance) against the commonly-used antimicrobial agents: ampicillin, amoxicillin, chloramphenicol, tetracycline, cotrimoxazole, nalidixic acid, sulfonamide, and neomycin, and were completely sensitive to ciprofloxacin. Eighteen resistance patterns against nine antimicrobial agents tested were observed in enteric pathogens. Resistance to ampicillin, amoxicillin, tetracycline, cotrimoxazole, and sulfonamide was the most frequent pattern. The common urinary pathogens, E. coli, Klebsiella pneumoniae, and Proteus mirabilis showed high rates of resistance to ampicillin, amoxicillin, cotrimoxazole, tetracycline, sulfonamide, trimethoprim, streptomycin, and carbenicillin. We recommend that physicians seek updated knowledge of the common antibiotic-sensitivity patterns when starting empirical antibiotic therapy in Sudanese patients with diarrhea or urinary tract infection.
|ISSN : ||0002-9637|
|Mesh Heading : ||Anti-Bacterial Agents Bacteria Bacterial Infections Ciprofloxacin Diarrhea Drug Resistance, Microbial Escherichia coli Humans Microbial Sensitivity Tests Shigella Sudan Urinary Tract Infections isolation & purification epidemiology microbiology pharmacology therapeutic use drug effects drug effects epidemiology|
|Mesh Heading Relevant : ||pharmacology therapeutic use drug effects drug therapy microbiology microbiology|