Toxocariasis in Japan.
Journal - Parasitology international (Netherlands )
Toxocariasis has long been considered a parasitic disease affecting pet owners and children who often play in sandboxes at public parks. Recent cases of this animal-borne infection, however, indicate that its clinical manifestations and etiologies are changing. In this article, we will describe the critical characteristic features of toxocariasis alongside the contributions of Japanese researchers to a better understanding of the disease.
|ISSN : ||1383-5769|
|Mesh Heading : ||Adolescent Adult Aged Aged, 80 and over Animals Child Child, Preschool Female Humans Infant Infant, Newborn Japan Male Middle Aged Toxocara Toxocara canis epidemiology diagnosis epidemiology parasitology physiopathology classification pathogenicity pathogenicity diagnosis epidemiology parasitology physiopathology|
|Mesh Heading Relevant : ||Larva Migrans, Visceral Toxocariasis|
Diffuse retinochoroiditis due to Baylisascaris procyonis in Monglian gerbils.
Journal - The Journal of parasitology (United States )
Baylisascaris procyonis, raccoon roundworm, causes a severe retinal lesion in humans. The lesion is termed as diffuse unilateral subacute neuroretinitis (DUSN). To understand the pathogenesis of B. procyonis in gerbils, we inoculated 17 embryonated eggs/g body weight of B. procyonis into 15 male Mongolian gerbils, Merionis ungiculatus, and monitored their fundi with an ophthalmoscope. Six of 15 gerbils (40%) showed severe retinitis with a sinuous track due to larval movement. The lesions extended across nearly half of the affected fundi. Histopathological examination revealed perivasculitis in the optic disk region, inflammatory proliferation of the pigment cells, and vitreitis in most cases. These findings were similar to those in human cases of DUSN, suggesting that gerbils might be a useful model for understanding the pathogenesis of B. procyonis infection in humans.
|ISSN : ||0022-3395|
|Mesh Heading : ||Animals Ascaridida Infections Ascaridoidea Disease Models, Animal Eye Infections, Parasitic Female Fundus Oculi Gerbillinae Male Retina Retinitis pathology pathology parasitology pathology pathology|
|Mesh Heading Relevant : ||parasitology pathogenicity parasitology parasitology|