K J Alcock -United Kingdom

University of Oxford

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Keywords

  • diagnosis genetics

  • Music Pitch Perception Speech Acoustics Time Perception genetics

  • Music diagnosis physiology physiology diagnosis physiology

Summary Information

  • Brain and language (3)
8,306,749
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Sources

Oral dyspraxia in inherited speech and language impairment and acquired dysphasia.
(2000)
Journal - Brain and language (UNITED STATES )

Abstract :

Half of the members of the KE family suffer from an inherited verbal dyspraxia. The affected members of the family have a lasting impairment in phonology and syntax. They were given various tests of oral praxis to investigate whether their deficit extends to nonverbal movements. Performance was compared to adult patients with acquired nonfluent dysphasia, those with comparable right-hemisphere lesions, and age-matched controls. Affected family members and patients with nonfluent dysphasia were impaired overall at performing oral movements, particularly combinations of movements. It is concluded that affected members of the KE family resemble patients with acquired dysphasia in having difficulties with oral praxis and that speech and language problems of affected family members arise from a lower level disorder.Copyright 2000 Academic Press.

ISSN : 0093-934X
Mesh Heading : Adolescent Adult Aged Aphasia, Broca Apraxias Brain Mapping Diagnosis, Differential Dominance, Cerebral Female Humans Male Middle Aged Neuropsychological Tests Phenotype Phonetics Semantics diagnosis physiology
Mesh Heading Relevant : diagnosis genetics
Pitch and timing abilities in inherited speech and language impairment.
(2000)
Journal - Brain and language (UNITED STATES )

Abstract :

Members of the KE family who suffer from an inherited developmental speech-and-language disorder and normal, age-matched, controls were tested on musical abilities, including perception and production of pitch and rhythm. Affected family members were not deficient in either the perception or production of pitch, whether this involved either single notes or familiar melodies. However, they were deficient in both the perception and production of rhythm in both vocal and manual modalities. It is concluded that intonation abilities are not impaired in the affected family members, whereas their timing abilities are impaired. Neither their linguistic nor oral praxic deficits can be at the root of their impairment in timing; rather, the reverse may be true.Copyright 2000 Academic Press.

ISSN : 0093-934X
Mesh Heading : Adolescent Adult Aged Apraxias Child Chromosome Aberrations Chromosome Disorders Dominance, Cerebral Female Genes, Dominant Humans Male Middle Aged Neuropsychological Tests Reference Values Sound Spectrography Voice Quality diagnosis genetics genetics genetics genetics
Mesh Heading Relevant : Music Pitch Perception Speech Acoustics Time Perception genetics
Pitch and timing abilities in adult left-hemisphere-dysphasic and right-hemisphere-damaged subjects.
(2000)
Journal - Brain and language (UNITED STATES )

Abstract :

The production and perception of pitch and rhythm were tested in patients with acquired unilateral left-hemisphere (LH) lesions (and subsequent motor dysphasia, n = 13), patients with unilateral right-hemisphere (RH) lesions (n = 14), and normal age-matched controls. While the LH dysphasic subjects were not generally impaired on the production or perception of pitch, they were grossly impaired on the production and perception of rhythm. The RH subjects, in contrast, were impaired on measures of pitch perception and production, including the discrimination and production of single notes and of melodies. It is concluded that the two hemispheres differ in their specialization for the perception and production of pitch and rhythm.Copyright 2000 Academic Press.

ISSN : 0093-934X
Mesh Heading : Adult Aged Aged, 80 and over Aphasia, Broca Brain Mapping Cerebral Cortex Dominance, Cerebral Female Humans Male Middle Aged Pitch Perception Sound Spectrography Stroke Time Perception Voice Quality physiopathology physiopathology physiopathology physiology
Mesh Heading Relevant : Music diagnosis physiology physiology diagnosis physiology


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