Ergonovine-testing-directed therapy and long-term outcome of sudden-death survivors with no apparent heart disease.
Journal - Cardiology (SWITZERLAND )
Coronary artery vasospasm, the most common cause of sudden death in patients with structurally normal hearts, is not well recognized. We describe 2 survivors of sudden death with ergonovine-inducible coronary artery vasospasm successfully treated long term with calcium channel blockers. Of the reported (17 worldwide) patients with documented vasospasm-mediated sudden cardiac death treated with calcium blockers, none have had a recurrent event. This is substantially less than the 6-month sudden-death rate of 18 % of untreated vasospasm. We advocate that ergonovine provocative testing of sudden-death survivors with structurally normal hearts, followed by appropriate therapy with calcium channel blockers, be the standard approach for these highly treatable patients.
|ISSN : ||0008-6312|
|Mesh Heading : ||Adult Calcium Channel Blockers Coronary Angiography Coronary Vasospasm Death, Sudden, Cardiac Ergonovine Female Humans Male Middle Aged Survivors therapeutic use drug therapy radiography diagnostic use|
|Mesh Heading Relevant : ||complications etiology|