Studies on the products of conversion of 4-ethoxycarbonylmethyl-1,2,4-triazoline-5-thione. VII. Synthesis of 4-beta-acetylaminoethyl derivatives of 1,2,4-triazoline-5-thione.
Journal - Acta poloniae pharmaceutica (Poland )
In the reaction of 4-ethoxycarbonylmethyl-1,2,4-triazoline-5-thione derivatives (Ia,b) with the primary amines the corresponding amides (IIa,b-IVa,b) have been formed. These amides were then undergone to reduction with LiAlH4 leading to the formation of corresponding amines (Va,b-VIIa,b). Then by means of the reaction with acetic anhydride these amines were transformed into corresponding acetylamine derivatives of 1,2,4-triazoline-5-thione (VIIIa,b-Xa,b).
|ISSN : ||0001-6837|
|Mesh Heading : ||Acetic Anhydrides Acetylation Amines Chemistry, Physical Physicochemical Phenomena Thioamides Thiones Triazoles chemistry chemistry|
|Mesh Heading Relevant : ||chemistry chemistry chemistry|