Chitosan beads loaded with essential oils in cosmetic formulations.
(2008)
Journal - International journal of cosmetic science
Abstract :
Presented in part at the XXVI Congreso Internacional de la Sociedad Farmace utica del Mediterra neo Latino, Medicamentos del siglo XXI: Innovadores y Gene ricos, Palma de Mallorca, September 16-18, 2004. The aim of this work is to evaluate the stability and release of chitosan beads loaded with volatile molecules of Mentha piperita essential oil (EO) in a cosmetic formulation. The ability of the beads to quickly release Mentha piperita EO during use of a cosmetic formulation such as bath foam is also assessed. The chitosan beads were produced with three different chitosan dispersions gelled with two different gelling solutions: (i) a 10% solution of sodium hydroxide (NaOH) and (ii) a 4% solution of sodium tripolyphosphate (TPP). A few properties of six bead samples loaded with Mentha piperita EO are assessed. The properties are morphology, size, swelling ability, encapsulation efficiency, stability in time, and fast release of Mentha piperita EO during the use phase of the cosmetic formulation.
Chitosan beads loaded with essential oils in cosmetic formulations.
(2006)
Journal - Journal of cosmetic science (United States )
Abstract :
The aim of this work is to evaluate the stability and release of chitosan beads loaded with volatile molecules of Mentha piperita essential oil (E.O.) in a cosmetic formulation. The ability of the beads to quickly release Mentha piperita E.O. during use of a cosmetic formulation such as a bath foam is also assessed. The chitosan beads were produced with three different chitosan dispersions gelled with two different gelling solutions: (a) a 10% solution of sodium hydroxide (NaOH) and (b) a 4% solution of sodium tripolyphosphate (TPP). A few properties of six bead samples loaded with Mentha piperita E.O. are assessed. The properties are morphology, size, swelling ability, encapsulation efficiency, stability in time, and fast release of Mentha piperita E.O. during the use phase of the cosmetic formulation.
| ISSN : | 1525-7886 |
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| Mesh Heading : | Mentha Polyphosphates Sodium Hydroxide Solutions Spectrophotometry, Ultraviolet chemistry chemistry |
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| Mesh Heading Relevant : | Chitosan Cosmetics |
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Physical properties of chitosan dispersions in glycolic acid.
(2004)
Journal - Farmaco (Società chimica italiana : 1989) (Italy )
Abstract :
Evaporation-freezing and rheological behaviour of chitosan dispersions at different temperatures and with different molecular weights using glycolic acid as anionic systems were studied. Chitosans of high, 2,000,000, medium, 750,000, and low, 70,000 molecular weight (hC, mC, and lC, respectively) were employed alone or as mixtures (hC/mC, hC/lC, and mC/lC 1:1, w/w). Different concentrations of glycols were added to these base dispersions (propylene glycol and glycerine) to investigate how the above physical properties change. The different rheological and evaporation-freezing behaviours of chitosan dispersions were related both to the molecular weight of chitosan and the vehicle composition of the dispersions. Particularly, the rheological study showed a pseudoplastic and shear thinning behaviour for all chitosan dispersions with flow index values n, tending to <1 at increasing molecular weights. Chitosans dispersions containing glycols showed lower apparent viscosity values than the base dispersions of the corresponding chitosans, but the water loss and the freezing point were lower especially for chitosan dispersions containing glycerine. This work presents a wide range of dispersion series from which to choose the most suitable to formulate pharmaceutical and cosmetic products.
| ISSN : | 0014-827X |
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| Mesh Heading : | Biocompatible Materials Chitosan Drug Delivery Systems Freezing Glycolates Keratolytic Agents Molecular Weight Polymers Rheology Temperature Time Factors Viscosity Volatilization chemistry chemistry |
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| Mesh Heading Relevant : | chemistry chemistry chemistry |
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Stability studies of new cosmetic formulations with vegetable extracts as functional agents.
(2001)
Journal - Farmaco (Società chimica italiana : 1989) (Italy )
Abstract :
A formulation study, using increasing amounts of Sepigel 305 as an emulsifier, has been carried out to find new O/W emulsions and value their stability also in presence of vegetable extracts. Stability results have been compared with those obtained from formulations described in the National Formulary of Italian Pharmacopoeia X and functionalised by us with the same vegetable extracts. By using centrifugation and accelerated ageing tests capable of bringing out the gelling and thermostability properties of Sepigel 305, the study emphasised that the new gel emulsions have a greater stability compared to the other formulations.
| ISSN : | 0014-827X |
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| Mesh Heading : | Anti-Infective Agents Centrifugation Cosmetics Drug Stability Emulsions Excipients Hydrogen-Ion Concentration Microbial Sensitivity Tests Odors Ointments Plant Extracts Rheology Temperature pharmacology |
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| Mesh Heading Relevant : | analysis analysis |
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Determination of bezafibrate concentration by high performance liquid-chromatography in serum of rats treated with lead nitrate.
(1999)
Journal - Farmaco (Società chimica italiana : 1989) (ITALY )
Abstract :
In the present study, the bezafibrate levels were measured in serum of rats treated with lead nitrate using a high performance liquid chromatography (HPLC) method. The results have shown that the peak corresponding to bezafibrate in the chromatogram is reduced in serum of rats treated with bezafibrate plus lead, indicating that lead treatment accelerates the metabolism of bezafibrate in rats.
| ISSN : | 0014-827X |
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| Mesh Heading : | Administration, Oral Animals Antilipemic Agents Bezafibrate Chromatography, High Pressure Liquid Drug Interactions Injections, Intravenous Lead Male Mitogens Nitrates Rats Rats, Wistar metabolism metabolism |
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| Mesh Heading Relevant : | blood blood pharmacology pharmacology pharmacology |
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Synthesis of cis- and trans- 2-arylmethylcycloalkylamines: potential dopaminergic agents.
(1997)
Journal - Farmaco (Società chimica italiana : 1989) (ITALY )
Abstract :
This paper reports the synthesis and the study of a few new diastereomeric arylmethylcycloalkylamines, tested as potential dopamine receptor active agents. New procedures for the stereospecific synthesis of the arylmethylcycloalkylamines were successfully experimented. All the considered compounds did not show any appreciable dopamine receptor activity.
| ISSN : | 0014-827X |
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| Mesh Heading : | Amines Animals Cycloparaffins Dopamine Agents Magnetic Resonance Spectroscopy Mass Spectrometry Rats Receptors, Dopamine Spectrophotometry, Infrared pharmacology pharmacology pharmacology drug effects |
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| Mesh Heading Relevant : | chemical synthesis chemical synthesis chemical synthesis |
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