Interpretation and reporting of positron emission tomography-computed tomographic scans.
Journal - Seminars in ultrasound, CT, and MR (United States )
Body oncology positron emission tomography-computed tomographic (PET-CT) exams are particularly complex and time-consuming studies to interpret and report. An integrated approach is required to provide the referring physician with the full clinical value of this combined modality. Special attention to the Positron Emission Tomography-Computed Tomographic Report Findings section and Impression section is necessary to insure all the information relevant to the patient's care are clearly communicated to the referring physicians.
|ISSN : ||0887-2171|
|Mesh Heading : ||Automatic Data Processing Humans Image Interpretation, Computer-Assisted Neoplasms Positron-Emission Tomography Tomography, X-Ray Computed diagnosis|
|Mesh Heading Relevant : ||methods methods|
Detection of clinically unexpected malignant and premalignant tumors with whole-body FDG PET: histopathologic comparison.
Journal - Radiology (United States )
PURPOSE: To determine the clinical importance and malignant potential of unexpected abnormal foci of hypermetabolism at fluorodeoxyglucose (FDG) positron emission tomography (PET) performed for evaluation of malignancy. MATERIALS AND METHODS: A total of 1,750 FDG PET scans were obtained to evaluate a variety of known or suspected malignancies. Each scan was evaluated for abnormal unexpected hypermetabolism based on unusual location (ie, foci that did not conform to the usual distribution of metastases given the primary tumor for which the PET scan was requested) and discrete focal nature of an abnormality. Unexpected findings were followed by pathologic confirmation and were considered clinically important if the final pathologic diagnosis was cancerous, precancerous, or noncancerous but had the potential for local destruction or systemic physiologic effects. RESULTS: On the basis of the normal spread pattern of the primary lesion, 58 abnormal unexpected foci of hypermetabolism were identified in 53 patients. Forty-five of these abnormalities were followed up with computed tomography (CT), magnetic resonance imaging, and/or mammography, and 42 had subsequent tissue confirmation at endoscopic, CT-guided, or surgical biopsy. Of 42 histopathologically confirmed abnormalities, 30 (71%) were either malignant or premalignant tumors that differed from the cancer for which the patient was originally scanned. Nine other suspicious abnormal foci proved benign and three represented false-positive findings, with no abnormal findings at endoscopy. Three of nine nonmalignant lesions were considered clinically important because of the potential for local destruction and/or systemic effects. CONCLUSION: The identification of unexpected foci of hypermetabolism at whole-body FDG PET may signal the presence of tumors that are unrelated to the neoplasm for which the patient was scanned. Findings of this study emphasize the need for follow-up of these abnormalities because the majority represent either malignant or premalignant neoplasms, which were not clinically apparent.Copyright RSNA, 2003
|ISSN : ||0033-8419|
|Mesh Heading : ||Aged Aged, 80 and over Biopsy Blood Glucose Energy Metabolism Female Fluorodeoxyglucose F18 Follow-Up Studies Humans Incidental Findings Male Middle Aged Neoplasm Metastasis Neoplasms Neoplasms, Multiple Primary Precancerous Conditions Sensitivity and Specificity Tomography, X-Ray Computed physiology diagnostic use radionuclide imaging pathology pathology pathology|
|Mesh Heading Relevant : ||Tomography, Emission-Computed metabolism radionuclide imaging radionuclide imaging radionuclide imaging|
Introduction to clinical positron emission tomography.
Journal - New Jersey medicine : the journal of the Medical Society of New Jersey (UNITED STATES )
Positron emission tomography (PET) scanning with [18F] fluorodeoxyglucose (FDG) has developed over 25 years into a valuable clinical tool used mainly for the evaluation of oncology patients. The purpose of this article is to provide an introduction to the basic scientific concepts of FDG-PET imaging as well as to illustrate its clinical utility.
|ISSN : ||0885-842X|
|Mesh Heading : ||Adenocarcinoma Adult Aged Aged, 80 and over Carcinoma, Bronchogenic Colonic Neoplasms Female Fluorodeoxyglucose F18 Hodgkin Disease Humans Lung Neoplasms Male Middle Aged Radiopharmaceuticals radionuclide imaging radionuclide imaging radionuclide imaging radionuclide imaging radionuclide imaging|
|Mesh Heading Relevant : ||Tomography, Emission-Computed diagnostic use diagnostic use|