TRAINING IN INNOVATIVE CANCER IMAGING TECHNOLOGIES
(2002)
Abstract :
The Department of Radiology, in conjunction with the Comprehensive Cancer Center at the University of Pennsylvania School of Medicine, is resubmitting a proposal for a Training Program in Innovative Cancer Imaging Technologies. The fundamental goal of the program is to develop quality, independent investigators in Radiology who will focus their scientific efforts in oncology research, goals which have been strengthened and clarified by the suggested revisions. The program will prepare postgraduate M.D.s in radiology programs (2/yr.) for academic radiology research using anatomic and physiologic imaging technologies to address issues in the detection, diagnosis, staging, monitoring of treatment, and progression of malignant lesion. In addition to training in the theory and implementation of magnetic resonance (MR), ultrasound, computed tomography (CT), optical tomography (OT), positron emission tomography (PET), and single photon emission computed tomography (SPECT), the trainees will be exposed to a broad spectrum of imaging research from coil and component design and the development of new technologies, to laboratory studies, translational research and clinical trials utilizing these imaging modalities. Research training will be accomplished through three categories of experiences: (21) preceptor-directed oncology imaging research; (2) laboratory and clinical research structured interactive seminars' and (3) attendance at scientific meetings and appropriate symposia. Participating faculty preceptors have active, funded laboratories and a broad base of experience in imaging and oncology research. The Advisory Committee to the training program will provide administrative guidance to the program director, evaluate program progress and suggest directions for future programmatic efforts. The progress of the trainees will be monitored carefully, both by the primary preceptor, as well as by the entire participating faculty. The primary research training facility is the Department of Radiology which, in addition to extensive MR facilities, has active research groups in metabolic MR, nuclear medicine, medical informatics, medical image processing for tomographic image reconstruction, and a center for the developing technology of optical imaging. In addition, the research and Clinical facilities of the Cancer Center, The Departments of Radiation Oncology, and Biochemistry and Biophysics, and the Hospital of the U.of Penn. will be used by the trainees. The extensive research resources in the Department of Radiology and the Cancer Center will ensure quality research training in a scientifically sound and cost-effective manner. This will enable the Department of Radiology to increase the number of young clinical investigators committed to investigative excellence in academic oncology research using imaging technology.
| Project Number : | 5T32CA065442-05 |
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| ICD : | NATIONAL CANCER INSTITUTE |
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| IRG : | CRME |
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TRAINING IN INNOVATIVE CANCER IMAGING TECHNOLOGIES
(2001)
| Project Number : | 1T32CA065442-01A2 |
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| ICD : | NATIONAL CANCER INSTITUTE |
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| IRG : | CRME |
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TRAINING IN INNOVATIVE CANCER IMAGING TECHNOLOGIES
(2001)
| Project Number : | 5T32CA065442-02 |
|---|
| ICD : | NATIONAL CANCER INSTITUTE |
|---|
| IRG : | CRME |
|---|
TRAINING IN INNOVATIVE CANCER IMAGING TECHNOLOGIES
(2001)
Abstract :
The Department of Radiology, in conjunction with the Comprehensive Cancer Center at the University of Pennsylvania School of Medicine, is resubmitting a proposal for a Training Program in Innovative Cancer Imaging Technologies. The fundamental goal of the program is to develop quality, independent investigators in Radiology who will focus their scientific efforts in oncology research, goals which have been strengthened and clarified by the suggested revisions. The program will prepare postgraduate M.D.s in radiology programs (2/yr.) for academic radiology research using anatomic and physiologic imaging technologies to address issues in the detection, diagnosis, staging, monitoring of treatment, and progression of malignant lesion. In addition to training in the theory and implementation of magnetic resonance (MR), ultrasound, computed tomography (CT), optical tomography (OT), positron emission tomography (PET), and single photon emission computed tomography (SPECT), the trainees will be exposed to a broad spectrum of imaging research from coil and component design and the development of new technologies, to laboratory studies, translational research and clinical trials utilizing these imaging modalities. Research training will be accomplished through three categories of experiences: (21) preceptor-directed oncology imaging research; (2) laboratory and clinical research structured interactive seminars' and (3) attendance at scientific meetings and appropriate symposia. Participating faculty preceptors have active, funded laboratories and a broad base of experience in imaging and oncology research. The Advisory Committee to the training program will provide administrative guidance to the program director, evaluate program progress and suggest directions for future programmatic efforts. The progress of the trainees will be monitored carefully, both by the primary preceptor, as well as by the entire participating faculty. The primary research training facility is the Department of Radiology which, in addition to extensive MR facilities, has active research groups in metabolic MR, nuclear medicine, medical informatics, medical image processing for tomographic image reconstruction, and a center for the developing technology of optical imaging. In addition, the research and Clinical facilities of the Cancer Center, The Departments of Radiation Oncology, and Biochemistry and Biophysics, and the Hospital of the U.of Penn. will be used by the trainees. The extensive research resources in the Department of Radiology and the Cancer Center will ensure quality research training in a scientifically sound and cost-effective manner. This will enable the Department of Radiology to increase the number of young clinical investigators committed to investigative excellence in academic oncology research using imaging technology.
| Project Number : | 5T32CA065442-03 |
|---|
| ICD : | NATIONAL CANCER INSTITUTE |
|---|
| IRG : | CRME |
|---|
TRAINING IN INNOVATIVE CANCER IMAGING TECHNOLOGIES
(2001)
Abstract :
The Department of Radiology, in conjunction with the Comprehensive Cancer Center at the University of Pennsylvania School of Medicine, is resubmitting a proposal for a Training Program in Innovative Cancer Imaging Technologies. The fundamental goal of the program is to develop quality, independent investigators in Radiology who will focus their scientific efforts in oncology research, goals which have been strengthened and clarified by the suggested revisions. The program will prepare postgraduate M.D.s in radiology programs (2/yr.) for academic radiology research using anatomic and physiologic imaging technologies to address issues in the detection, diagnosis, staging, monitoring of treatment, and progression of malignant lesion. In addition to training in the theory and implementation of magnetic resonance (MR), ultrasound, computed tomography (CT), optical tomography (OT), positron emission tomography (PET), and single photon emission computed tomography (SPECT), the trainees will be exposed to a broad spectrum of imaging research from coil and component design and the development of new technologies, to laboratory studies, translational research and clinical trials utilizing these imaging modalities. Research training will be accomplished through three categories of experiences: (21) preceptor-directed oncology imaging research; (2) laboratory and clinical research structured interactive seminars' and (3) attendance at scientific meetings and appropriate symposia. Participating faculty preceptors have active, funded laboratories and a broad base of experience in imaging and oncology research. The Advisory Committee to the training program will provide administrative guidance to the program director, evaluate program progress and suggest directions for future programmatic efforts. The progress of the trainees will be monitored carefully, both by the primary preceptor, as well as by the entire participating faculty. The primary research training facility is the Department of Radiology which, in addition to extensive MR facilities, has active research groups in metabolic MR, nuclear medicine, medical informatics, medical image processing for tomographic image reconstruction, and a center for the developing technology of optical imaging. In addition, the research and Clinical facilities of the Cancer Center, The Departments of Radiation Oncology, and Biochemistry and Biophysics, and the Hospital of the U.of Penn. will be used by the trainees. The extensive research resources in the Department of Radiology and the Cancer Center will ensure quality research training in a scientifically sound and cost-effective manner. This will enable the Department of Radiology to increase the number of young clinical investigators committed to investigative excellence in academic oncology research using imaging technology.
| Project Number : | 5T32CA065442-04 |
|---|
| ICD : | NATIONAL CANCER INSTITUTE |
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| IRG : | CRME |
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ANGIOGRAPHIC DIAGNOSIS AND CONTROL OF GI BLEEDING
(1981)
Abstract :
As an outgrowth of the investigators' description of the technique of angiographically demonstrating sites of gastrointestinal bleeding, as well as their control by intraarterial infusion of vasopressin, many questions have arisen regarding present techniques. The investigators are requesting renewal of their present grant to further refine and develop new approaches to this difficult and important problem. During the next three years, the investigators will attempt to evaluate resons for failure of transcatheter therapy to control bleeding in some patients. In addition, we will attempt to better define the role of angiography in the treatment of bleeding using a prospective randomized clinical study. The role of radioisotopes in the demonstration of bleeding sites will be investigated in the hopes of finding a relatively simple method of localizing acute hemorrhage. The efficacy of systemic vasopressin compared to intraarterial vasopressin in the treatment of arterial bleeding will be examined. Investigation will continue on colonic angiodysplasia concerning the histologic nature, relative frequency and etiology of this lesion. An attempt will be made to determine the safety of long term infusions of vasopressin in the hepatic artery. The role of contraction of the wall of the esophagus, stomach and bowel in the control of bleeding will be examined.
| Project Number : | 5R01AM020604-02 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
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| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY, GASTROINTESTINAL CIRCULATORY DISORDERS, HEMORRHAGE, GASTROINTESTINAL, GASTROINTESTINAL DISORDERS DIAGNOSIS (INCL EXAMS), RADIATION STUDY SECTION PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN MAMMALS, CARNIVORES, DOGS |
|---|
ANGIOGRAPHIC DIAGNOSIS AND CONTROL OF GI BLEEDING
(1981)
Abstract :
As an outgrowth of the investigators' description of the technique of angiographically demonstrating sites of gastrointestinal bleeding, as well as their control by intraarterial infusion of vasopressin, many questions have arisen regarding present techniques. The investigators are requesting renewal of their present grant to further refine and develop new approaches to this difficult and important problem. During the next three years, the investigators will attempt to evaluate resons for failure of transcatheter therapy to control bleeding in some patients. In addition, we will attempt to better define the role of angiography in the treatment of bleeding using a prospective randomized clinical study. The role of radioisotopes in the demonstration of bleeding sites will be investigated in the hopes of finding a relatively simple method of localizing acute hemorrhage. The efficacy of systemic vasopressin compared to intraarterial vasopressin in the treatment of arterial bleeding will be examined. Investigation will continue on colonic angiodysplasia concerning the histologic nature, relative frequency and etiology of this lesion. An attempt will be made to determine the safety of long term infusions of vasopressin in the hepatic artery. The role of contraction of the wall of the esophagus, stomach and bowel in the control of bleeding will be examined.
| Project Number : | 5R01AM020604-03 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY, GASTROINTESTINAL CIRCULATORY DISORDERS, HEMORRHAGE, GASTROINTESTINAL, GASTROINTESTINAL DISORDERS DIAGNOSIS (INCL EXAMS), RADIATION STUDY SECTION PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN MAMMALS, CARNIVORES, DOGS |
|---|
ANGIOGRAPHIC DIAGNOSIS AND CONTROL OF GI BLEEDING
(1981)
Abstract :
As an outgrowth of the investigators description of the technique of angiographically demonstrating sites of gastrointestinal bleeding, as well as their control by intraarterial infusion of vasopressin, many questions have arisen regarding present techniques. The investigators are requesting renewal of their present grant to further refine and develop new approaches to this difficult and important problem. During the next three years, the investigators will attempt to evaluate resons for failure of transcatheter therapy to control bleeding in some patients. In addition, we will attempt to better define the role of angiography in the treatment of bleeding using a prospective randomized clinical study. The role of radioisotopes in the demonstration of bleeding sites will be investigated in the hopes of finding a relatively simple method of localizing acute hemorrhage. The efficacy of systemic vasopressin compared to intraarterial vasopressin in the treatment of arterial bleeding will be examined. Investigation will continue on colonic angiodysplasia concerning the histologic nature, relative frequency and etiology of this lesion. An attempt will be made to determine the safety of long term infusions of vasopressin in the hepatic artery. The role of contraction of the wall of the esophagus, stomach and bowel in the control of bleeding will be examined.
| Project Number : | 1R01AM020604-01A1 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY, GASTROINTESTINAL CIRCULATORY DISORDERS, HEMORRHAGE, GASTROINTESTINAL, GASTROINTESTINAL DISORDERS DIAGNOSIS (INCL EXAMS), RADIATION STUDY SECTION PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN MAMMALS, CARNIVORES, DOGS |
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NUCLEAR MEDICINE
(1978)
| Project Number : | 5T01GM001762-09 |
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| ICD : | NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES |
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| IRG : | RDL |
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NUCLEAR MEDICINE
(1978)
| Project Number : | 5T01GM001762-10 |
|---|
| ICD : | NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES |
|---|
| IRG : | RDL |
|---|
ANGIOGRAPHIC DIAGNOSIS AND CONTROL OF GI BLEEDING
(1977)
Abstract :
As an outgrowth of the Investigator's description of the technique of angiographically demonstrating sites of gastrointestinal bleeding many questions have arisen regarding the present techniques. The investigators are requesting renewal of their present grant so as to further refine present and develop newer approaches to this difficult and important problem. During the next twelve months, the investigators will attempt to improve radiographic and catheterization techniques of the examination by the use of magnification angiography. In addition, they will evaluate nonthrombogenic catheter materials and attempt to consistently develop methods of superselective catheterization and also evaluate a simple radiographic method of assessing blood flow in the mesenteric circulation. Another specific aim during the next grant period will be to try to answer the question of how long infusions are necessary to satisfactorily control arterial and venous bleeding. We will also attempt to determine the effect on the liver of hepatic arterial infusion of vasopressin. Various mechanical means of controlling gastrointestinal hemorrhage will also be evaluated which will include intraarterial radiofrequency coagulation, balloon catheters, and injectible silastic catheters.
| Project Number : | 7R01AM019453-01 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY*, GASTROINTESTINAL CIRCULATORY DISORDERS, HEMORRHAGE, GASTROINTESTINAL, GASTROINTESTINAL DISORDERS DIAGNOSIS (INCL EXAMS)*, LIVER CIRCULATORY DISORDERS, PORTAL HYPERTENSION, RADIATION STUDY SECTION, SURGERY, PREOPERATIVE, catheterization CARDIOVASCULAR AGENTS, VASOACTIVE AGENTS (GENERAL), CARDIOVASCULAR DISORDERS DIAGNOSIS, BLOOD FLOW MEASUREMENTS*, CARDIOVASCULAR FUNCTION, BLOOD FLOW, PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN DOSAGE AND ROUTE, INFUSIONS ARTERIAL, HUMAN, CLINICAL, IMMUNOLOGICAL TESTS AND IMMUNOASSAY, RADIOIMMUNOASSAY*, MAMMALS, CARNIVORES, DOGS*, MAMMALS, LAGOMORPHS* |
|---|
ANGIOGRAPHIC DIAGNOSIS AND CONTROL OF GI BLEEDING
(1976)
| Project Number : | 2R01AM016026-03 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY*, GASTROINTESTINAL CIRCULATORY DISORDERS, HEMORRHAGE, GASTROINTESTINAL, LIVER CIRCULATORY DISORDERS, PORTAL HYPERTENSION, SURGERY, PREOPERATIVE CARDIOVASCULAR AGENTS, VASOACTIVE AGENTS (GENERAL), CARDIOVASCULAR FUNCTION, BLOOD FLOW, DIAGNOSIS, DIAGNOSTIC TESTS*, GASTROINTESTINAL CIRCULATORY DISORDERS, PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN, RADIATION STUDY SECTION HUMAN, CLINICAL*, MAMMALS, CARNIVORES, DOGS* |
|---|
ANGIOGRAPHIC DIAGNOSIS AND CONTROL OF GI BLEEDING
(1976)
Abstract :
As an outgrowth of the investigator's description of the technique of angiographically demonstrating sites of gastrointestinal bleeding as well as their control by the intra-arterial infusion of Vasopressin, many questions have arisen regarding the present techniques. The investigators are requesting renewal of their present grant, so as to further refine present and develop newer approaches to this difficult and important problem. During the next three years, the investigators will attempt to improve radiographic and catheterization techniques of the examination by the use of magnification angiography. In addition, they will evaluate nonthrombogenic catheter materials, and attempt to consistently develop methods of superselective catheterization and also evaluate a simple radiographic method of assessing blood flow in the mesenteric circulation. Another specific aim during the next grant period will be to try to answer the question of how long infusions are necessary to satisfactorily control arterial and venous bleeding. We will also attempt to determine the effect on the liver of hepatic arterial infusion of vasopressin. Various mechanical means of controlling gastro-intestinal hemorrhage will also be evaluated, which will include intraarterial radiofrequency coagulation, balloon catheters and injectable silastic catheters. Attempts will also be made to determine whether the superior mesenteric artery infusion with vasopressin results in a redistribution of total blood flow so as to increase renal perfusion of patients with Type II hepatorenal syndrome.
| Project Number : | 5R01AM016026-04 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY*, GASTROINTESTINAL CIRCULATORY DISORDERS, HEMORRHAGE, GASTROINTESTINAL, LIVER CIRCULATORY DISORDERS, PORTAL HYPERTENSION, SURGERY, PREOPERATIVE CARDIOVASCULAR AGENTS, VASOACTIVE AGENTS (GENERAL), CARDIOVASCULAR FUNCTION, BLOOD FLOW, DIAGNOSIS, DIAGNOSTIC TESTS*, GASTROINTESTINAL CIRCULATORY DISORDERS, PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN, RADIATION STUDY SECTION HUMAN, CLINICAL*, MAMMALS, CARNIVORES, DOGS* |
|---|
ANGIOGRAPHIC DIAGNOSIS AND CONTROL OF GI BLEEDING
(1975)
Abstract :
As an outgrowth of the investigator's description of the technique of angiographically demonstrating sites of gastrointestinal bleeding as well as their control by the intra-arterial infusion of vasopressin, many questions have arisen regarding the present techniques. The investigators are requesting renewal of their present grant, so as to further refine present and develop newer approaches to this difficult and important problem. During the next three years, the investigators will attempt to improve radiographic and catheterization techniques of the examination by the use of magnification angiography. In addition, they will evaluate nonthrombogenic catheter materials, and attempt to consistently develop methods of superselective catheterization and also evaluate a simple radiographic method of assessing blood flow in the mesenteric circulation. Another specific aim during the next grant period will be to try to answer the question of how long infusions are necessary to satisfactorily control arterial and venous bleeding. We will also attempt to determine the effect on the liver of hepatic arterial infusion of vasopressin. Various mechanical means of controlling gastrointestinal hemorrhage will also be evaluated, which will include intraarterial radiofrequency coagulation, balloon catheters and injectable silastic catheters. Attempts will also be made to determine whether the superior mesenteric artery infusion with vasopressin results in a redistribution of total blood flow so as to increase renal perfusion of patients with Type II hepatorenal syndrome.
| Project Number : | 5R01AM016026-05 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY*, GASTROINTESTINAL CIRCULATORY DISORDERS, HEMORRHAGE, GASTROINTESTINAL, GASTROINTESTINAL DISORDERS DIAGNOSIS (INCL EXAMS)*, LIVER CIRCULATORY DISORDERS, PORTAL HYPERTENSION, RADIATION STUDY SECTION, SURGERY, PREOPERATIVE CARDIOVASCULAR AGENTS, VASOACTIVE AGENTS (GENERAL), CARDIOVASCULAR FUNCTION, BLOOD FLOW, MAMMALS, LAGOMORPHS*, PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN, catheterization HUMAN, CLINICAL, IMMUNOLOGICAL TESTS AND IMMUNOASSAY, RADIOIMMUNOASSAY*, MAMMALS, CARNIVORES, DOGS* |
|---|
PREOPERATIVE SITES OF GASTROINTESTINAL BLEEDING
(1973)
| Project Number : | 5R01AM016026-02 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|
| Project Terms : | CARDIOVASCULAR DISORDERS, HEMORRHAGE, CARDIOVASCULAR VISUALIZATION, ANGIOGRAPHY*, GASTROINTESTINAL DISORDERS, PEPTIC ULCER, LIVER CIRCULATORY DISORDERS, PORTAL HYPERTENSION, SURGERY, PREOPERATIVE CARDIOVASCULAR AGENTS, VASOACTIVE AGENTS (GENERAL), CARDIOVASCULAR SYSTEM, ARTERIES, CARDIOVASCULAR SYSTEM, ARTERIES, ABDOMINAL ARTERIES, DIAGNOSIS, DIAGNOSTIC TESTS*, GASTROINTESTINAL CIRCULATORY DISORDERS, PITUITARY-DIENCEPHALON HORMONES, VASOPRESSIN, RADIATION STUDY SECTION HUMAN, CLINICAL*, MAMMALS, CARNIVORES, DOGS* |
|---|
PREOPERATIVE SITES OF GASTROINTESTINAL BLEEDING
(1973)
| Project Number : | 7R01AM016026-01 |
|---|
| ICD : | NAT INST OF ARTHRITIS, DIABETES, DIGESTIVE & KIDNEY DISEASES |
|---|
| IRG : | RAD |
|---|