Hypothetical biotechnology companies: A role-playing student centered activity for undergraduate science students.
Journal - Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology (United States )
Science students leaving undergraduate programs are entering the biotechnology industry where they are presented with issues which require integration of science content. Students find this difficult as through-out their studies, most content is limited to a single subdiscipline (e.g., biochemistry, immunology). In addition, students need knowledge of the ethical, economic, and legal frame work in which the industry operates. This article presents an approach to deliver these outcomes in a collaborative and active learning modality which promotes deep learning. In the model, groups of final year undergraduate students form hypothetical biotechnology companies and identify real issues of interest to industry, make integrative team decisions, use professional level technology, and develop appropriate communication skills. The final successful teaching paradigm was based on self reflection, observation, and student feedback to ensure appropriate attainment of content, group work skills and increased confidence in professional decision-making. It is these outcomes which will facilitate life long learning skills, a major outcome applicable for all tertiary education.Copyright © 2011 Wiley Periodicals, Inc.
|ISSN : ||1539-3429|
|Mesh Heading : ||Biotechnology Curriculum Decision Making Humans Problem-Based Learning Students Teaching methods|
|Mesh Heading Relevant : ||Role Playing education psychology methods|
Amplification of DNA encoding entire type I polyketide synthase domains and linkers from streptomyces species.
Journal - Current microbiology (United States )
Polyketides are a group of bioactive compounds from bacteria, plants, and fungi. To increase the availability of analogs for testing, the active sites of polyketide synthases are often substituted with homologous domains having altered substrate specificities. This study reports the design of polymerase chain reaction primers that enables isolation of entire active site domains from type I polyketide synthases with native interdomain linkers. This bypasses the need for further genetic screening to obtain functional units for use in genetic engineering. This is especially important in bioprospecting projects exploring new environments for bioresources.
|ISSN : ||0343-8651|
|Mesh Heading : ||Antifungal Agents Aspergillus niger Binding Sites DNA Primers Genome, Bacterial Polyketide Synthases Polymerase Chain Reaction Protein Structure, Tertiary Streptomyces pharmacology drug effects genetics methods genetics|
|Mesh Heading Relevant : ||Soil Microbiology chemistry genetics enzymology|