Sherif B Abdel Ghani

University of Southampton

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Keywords

Microwaves chemical synthesis pharmacology chemical synthesis pharmacology

Summary Information

Bioorganic & medicinal chemistry letters (1)

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Sources

Microwave-assisted synthesis and antimicrobial activities of flavonoid derivatives.

(2008)

Journal - Bioorganic & medicinal chemistry letters (England )

Abstract :

Eleven flavonoid derivatives were synthesised using a modified Baker-Venkataraman rearrangement, and subsequent microwave-assisted closure of the heterocyclic ring. All of the synthetic compounds displayed antifungal activity against Aspergillus niger and Fusarium oxysporium, and two of the synthetic flavonoid analogues exhibited significant activity against methicillin-resistant Staphylococcus aureus.

ISSN :	1464-3405
Mesh Heading :	Anti-Infective Agents Aspergillus niger Flavonoids Fusarium Methicillin Resistance Microbial Sensitivity Tests Staphylococcus aureus drug effects drug effects drug effects
Mesh Heading Relevant :	Microwaves chemical synthesis pharmacology chemical synthesis pharmacology