J R Abbott -United States Of America

University of Florida

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Summary Information

  • Veterinary immunology and immunopathology (1)
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Sources

Evolutionarily conserved T-cell epitopes on FIV for designing an HIV/AIDS vaccine.
(2011)
Journal - Veterinary immunology and immunopathology (Netherlands )

Abstract :

This review will discuss the current state of the human HIV-1 vaccine trials including the safety consideration of vaccine composition and difficulties in determining and defining protective immunity and epitopes to HIV-1. Vaccines in animal models of lentivirus infection are compared. In particular, the findings from the prototype FIV vaccine and the HIV-1 protein immunizations studies in cats are discussed, as well as the resulting research regarding a potential HIV-1 vaccine design based on evolutionarily conserved T-cell epitopes.Copyright © 2011 Elsevier B.V. All rights reserved.

ISSN : 1873-2534


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