Macromolecular structure information and databases. The EU BRIDGE Database Project Consortium.
Journal - Trends in biochemical sciences (ENGLAND )
The current status and future outlook of macromolecular structure databases and information handling, with particular reference to European databases, are reviewed. Issues concerning the efficiency with which data are represented, validated, archived and accessed are discussed in view of the fast growing body of information on structures of biological macromolecules.
|ISSN : ||0968-0004|
|Mesh Heading : ||Europe Reproducibility of Results|
|Mesh Heading Relevant : ||Databases, Factual Macromolecular Substances|
An object-oriented database for protein structure analysis.
Journal - Protein engineering (ENGLAND )
An object-oriented database system has been developed which is being used to store protein structure data. The database can be queried using the logic programming language Prolog or the query language Daplex. Queries retrieve information by navigating through a network of objects which represent the primary, secondary and tertiary structures of proteins. Routines written in both Prolog and Daplex can integrate complex calculations with the retrieval of data from the database, and can also be stored in the database for sharing among users. Thus object-oriented databases are better suited to prototyping applications and answering complex queries about protein structure than relational databases. This system has been used to find loops of varying length and anchor positions when modelling homologous protein structures.
|ISSN : ||0269-2139|
|Mesh Heading : ||Amino Acid Sequence Chemical Phenomena Chemistry Protein Conformation|
|Mesh Heading Relevant : ||Information Systems Proteins|