COMPARISON OF THREE LEVELS OF METHADONE INTERVENTION
(1994)
Abstract :
Intravenous drug users and their sexual partners are a population at major risk for HIV/AIDS because they often share unclean needles and engage in unprotected sex. Since AIDS is lethal, immediate intervention is needed to reduce risk behaviors. The vast majority of opiate addicts use intravenous administration and methadone treatment is the primary mode of treating such addicts. Major goals of this proposal are to expand publicly funded methadone treatment capacity by 180 slots which is a 100 percent increase and to evaluate the impact of various models of supportive services on drug use and HIV/AIDS risk behaviors. The 312 subjects enrolled in this project will be randomly assigned to one of three treatment formats and within each level to one of two modes of managing positive urinalysis results. The three levels of methadone services are: 1)"enhanced" (mandatory individual counseling, treatment planning and weekly group therapy with psychiatric consultation available); 2)"standard" (mandatory individual counseling and treatment planning with psychiatric consultation available); 3)"medication only" (only 15 minute check-in counseling available). Within each level of methadone service two protocols for managing positive urinalysis results will be used. Contingency contracting with a maximum consequence of administrative discharge will be used with half of each group. For the remainder of each group, positive urine tests will result only in additional therapeutic discussion. Data on risk behavior and drug use will be gathered on initial entry into the study and at 6, 12, and 18 months, using structured interviews and physical exams. Optional HIV testing will be available. Changes in risk behavior, drug use patterns and HIV serostatus will be used to assess the effectiveness of the various interventions and to determine if one is superior to the others.
| Project Number : | 1R18DA006104-01 |
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| ICD : | NATIONAL INSTITUTE ON DRUG ABUSE |
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| IRG : | SRCD |
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| Project Terms : | DRUGS ABUSE, DRUGS ADDICTION, DRUGS ABUSE, DRUGS ADDICTION TREATMENT AND REHABILITATION, CHEMOTHERAPY, DRUGS ABUSE, INTRAVENOUS DRUG ABUSERS, PHENYLALKYLAMINES, METHADONE, THERAPY EVALUATION, HUMAN IMMUNOPATHOLOGY, IMMUNOLOGIC DEFICIENCY DISORDERS, ACQUIREDDEFICIENCY DISORDERS, HIV INFECTION, MENTAL HEALTH SERVICES, COUNSELING, PSYCHOLOGY, BEHAVIOR, COMPULSIVE, RISK-TAKING-GAMBLING CHEMISTRY, CLINICAL, URINE CHEMICAL ANALYSIS, HUMAN, CLINICAL |
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COMPARISON OF THREE LEVELS OF METHADONE INTERVENTION
(1994)
Abstract :
Intravenous drug users and their sexual partners are a population at major risk for HIV/AIDS because they often share unclean needles and engage in unprotected sex. Since AIDS is lethal, immediate intervention is needed to reduce risk behaviors. The vast majority of opiate addicts use intravenous administration and methadone treatment is the primary mode of treating such addicts. Major goals of this proposal are to expand publicly funded methadone treatment capacity by 180 slots which is a 100 percent increase and to evaluate the impact of various models of supportive services on drug use and HIV/AIDS risk behaviors. The 312 subjects enrolled in this project will be randomly assigned to one of three treatment formats and within each level to one of two modes of managing positive urinalysis results. The three levels of methadone services are: 1)"enhanced" (mandatory individual counseling, treatment planning and weekly group therapy with psychiatric consultation available); 2)"standard" (mandatory individual counseling and treatment planning with psychiatric consultation available); 3)"medication only" (only 15 minute check-in counseling available). Within each level of methadone service two protocols for managing positive urinalysis results will be used. Contingency contracting with a maximum consequence of administrative discharge will be used with half of each group. For the remainder of each group, positive urine tests will result only in additional therapeutic discussion. Data on risk behavior and drug use will be gathered on initial entry into the study and at 6, 12, and 18 months, using structured interviews and physical exams. Optional HIV testing will be available. Changes in risk behavior, drug use patterns and HIV serostatus will be used to assess the effectiveness of the various interventions and to determine if one is superior to the others.
| Project Number : | 5R18DA006104-02 |
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| ICD : | NATIONAL INSTITUTE ON DRUG ABUSE |
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| IRG : | SRCD |
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| Project Terms : | DRUGS ABUSE, DRUGS ADDICTION, DRUGS ABUSE, DRUGS ADDICTION TREATMENT AND REHABILITATION, CHEMOTHERAPY, DRUGS ABUSE, INTRAVENOUS DRUG ABUSERS, PHENYLALKYLAMINES, METHADONE, THERAPY EVALUATION, HUMAN IMMUNOPATHOLOGY, IMMUNOLOGIC DEFICIENCY DISORDERS, ACQUIREDDEFICIENCY DISORDERS, HIV INFECTION, MENTAL HEALTH SERVICES, COUNSELING, PSYCHOLOGY, BEHAVIOR, COMPULSIVE, RISK-TAKING-GAMBLING CHEMISTRY, CLINICAL, URINE CHEMICAL ANALYSIS, HUMAN, CLINICAL |
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