Robert R Althoff -United States Of America

University of Vermont College of Medicine

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Keywords

  • Problem Solving Thinking psychology

  • genetics genetics

  • Attention Deficit Disorder with Hyperactivity Questionnaires

Summary Information

  • Journal of the American Academy of Child and Adolescent Psychiatry (3)
  • Twin research and human genetics : the official journal of the International Society for Twin Studies (1)
8,306,749
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Sources

Dysregulated children reconsidered.
(2010)
Journal - Journal of the American Academy of Child and Adolescent Psychiatry (United States )
ISSN : 1527-5418
In this issue/abstract thinking: parenting..
(2008)
Journal - Journal of the American Academy of Child and Adolescent Psychiatry (United States )
ISSN : 1527-5418
Mesh Heading : Adolescent Child Concept Formation Humans Parenting
Mesh Heading Relevant : Problem Solving Thinking psychology
Advanced twin designs.
(2008)
Journal - Journal of the American Academy of Child and Adolescent Psychiatry (United States )
ISSN : 1527-5418
Mesh Heading : Adolescent Child Diseases in Twins Epigenesis, Genetic Humans Mental Disorders Phenotype Sex Factors Social Environment Twins, Dizygotic Twins, Monozygotic psychology genetics psychology genetics psychology genetics psychology
Mesh Heading Relevant : genetics genetics
The latent class structure of ADHD is stable across informants.
(2006)
Journal - Twin research and human genetics : the official journal of the International Society for Twin Studies (Australia )

Abstract :

Previous studies have looked at the structure of attention-deficit/hyperactivity disorder (ADHD) using latent class analysis (LCA) of Child Behavior Checklist (CBCL) or Diagnostic and Statistical Manual of Mental Disorders (DSM) symptom structure. These studies have identified distinct classes of children with inattentive, hyperactive, or combined subtypes and have used these classes to refine genetic analyses. The objective of the current report is to determine if the latent class structure of ADHD subtypes is consistent across informant using the Conners' Rating Scales (CRS). LCA was applied to CRS forms from mother, father, and teacher reports of 1837, 1329 and 1048 latency aged Dutch twins, respectively. The optimal solution for boys was a 5-class solution for mothers, a 3-class solution for fathers, and a 4-class solution for teachers. For girls, a 4-class solution for mothers and a 3-class for fathers and teachers was optimal. Children placed into a class by one informant had markedly increased odds ratio of being placed into the same or similar class by the other informants. Results from LCA using Dutch twins with the CRS show stability across informants suggesting that more stable phenotypes may be accessible for genotyping using a multi-informant approach.

ISSN : 1832-4274
Mesh Heading : Adult Child Diagnostic and Statistical Manual of Mental Disorders Female Humans Male Netherlands Psychiatric Status Rating Scales classification epidemiology genetics
Mesh Heading Relevant : Attention Deficit Disorder with Hyperactivity Questionnaires


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