Identification of a new allele, HLA-DRB5*0113, through three different molecular biology techniques.
(2006)
Journal - Tissue antigens (Denmark )
Abstract :
A new HLA-DRB5 allele, HLA-DRB5*0113, has been identified in an Italian patient during routine HLA typing in order to activate a bone marrow donor search. HLA typing was performed by different molecular biology techniques, and the results showed that the HLA-DRB5*0113 allele differs from HLA-DRB5*010101 allele for three nucleotide substitutions at codons 57 (GAC-->GAT; Asp) and 58 (GCT-->GAG; Ala-->Glu) of exon 2.
| ISSN : | 0001-2815 |
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| Mesh Heading : | Alanine Alleles Amino Acid Sequence Amino Acid Substitution Base Sequence Bone Marrow Transplantation Glutamic Acid HLA-DR Antigens Histocompatibility Testing Humans Male Middle Aged Molecular Sequence Data Mutation chemistry genetics chemistry genetics |
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| Mesh Heading Relevant : | immunology genetics methods |
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Identification of a new HLA-DRB1 allele in three members of an Italian family.
(2004)
Journal - Tissue antigens (Denmark )
Abstract :
Abstract A new human leucocyte antigen (HLA)-DRB1 allele, HLA-DRB1*1149, has been identified in three members of an Italian family during routine sequence based typing. This new allele differs from HLA-DRB1*110101 only for a single nucleotide substitution at position 113 of exon 2 resulting in an amino acid change from Valine (GTG) to Alanine (GCG) at codon 38.
| ISSN : | 0001-2815 |
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| Mesh Heading : | Amino Acid Sequence Amino Acid Substitution Base Sequence HLA-DR Antigens Humans Italy Molecular Sequence Data Sequence Alignment |
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| Mesh Heading Relevant : | Alleles genetics |
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